Alfresco Tomcat JVM Tuning

I have an Alfresco installation with Tomcat server. Which file shall I use to setup JAVA_OPTS for tomcat?

The JAVA_OPTS is not set in alfresco.sh or catalina.sh. Instead, it is in tomcat/scripts/ctl.sh. Stop tomcat, make necessary changes and restart tomcat. You can verify it by

sudo ps -ef | grep java